Mycosis fungoides presenting as symmetric concentric patches mimicking figurate erythema
نویسندگان
چکیده
EAC: erythema annulare centrifugum MF: mycosis fungoides TCR: T-cell receptor CASE REPORT A 52-year-old white male presented to outpatient dermatology clinic for evaluation of a 4-year history of a recurrent, intermittent rash that appeared as symmetrically distributed, red annular patches on nonesun-exposed areas of his trunk and extremities. The lesions gradually expanded in concentric rings with scale over several months. The affected areas were mildly pruritic, and he experienced arthralgias with each flare. His medical history was noncontributory, and his only medication was a proton pump inhibitor, which he had been taking for many years. At an outside facility, Lyme disease testing was negative, and he was given the initial clinical diagnosis of erythema annulare centrifugum (EAC) and was treated with topical and systemic corticosteroids, which provided only temporary improvement. On examination, the bilateral upper and lower extremities had pink-red, symmetric, concentric annular patches with trailing scale covering 10% to 15% of his body surface area (Fig 1). There was no palpable cervical or axillary lymphadenopathy. Clinically, the differential diagnosis included EAC, erythema gyratum repens, tinea corporis, and mycosis fungoides (MF). Results of laboratory investigations were within normal limits. A punch biopsy and a broad shave
منابع مشابه
[Approaches to the dermatopathologic diagnosis of figurate lesions].
Both clinical and pathologic findings must be considered when diagnosing figurate skin lesions, which are often seen in routine practice. Although a skin biopsy may sometimes be diagnostic, more often the information provided is nonspecific. In an attempt to offer an approach to diagnosing these dermatoses, we have classified annular lesions according to the presence of lymphocytic, neutrophili...
متن کاملCD4/CD8 double-negative mycosis fungoides mimicking erythema gyratum repens in a patient with underlying lung cancer.
A 73-year-old Japanese man presented with a 10-year history of worsening, itchy, erythematous eruptions on his trunk and extremities. Dermatological examination revealed concentric, slightly infiltrated, annular, red patches and plaques, closely resembling EGR, on his chest, abdomen and extremities (Fig. 1). The lesions were not painful. Microscopy and culture excluded the presence of a mycotic...
متن کاملCluster of differentiation (CD) markers in erythrodermic patients: A case series study
Background: Erythroderma is an inflammatory disorder. It has various differential diagnoses, among which one of the most important is mycosis fungoides. Erythroderma itself can be a challenging disorder. Diagnosis of a mycosis fungoides patient presenting with erythroderma specially requires a careful assessment of the peripheral blood. Studies such as CD markers can lead to a more accura...
متن کاملDemographic and Clinical Features of Mycosis Fungoides in Tabriz, Iran
Dear Editor, Mycosis fungoides is the most common type of cutaneous T cell lymphoma with a reported incidence of 0.5 cases per 100,000 people per year.1 The cause of mycosis fungoides is still unknown; however genetic and environmental factors have been implicated as possible pathologic factors.2 The disease might also be associated with human T cell lymphotropic virus type 1,3 which is endemic...
متن کاملCluster of differentiation (CD) markers in erythrodermic patients: A case series study
Background: Erythroderma is an inflammatory disorder. It has various differential diagnoses, among which one of the most important is mycosis fungoides. Erythroderma itself can be a challenging disorder. Diagnosis of a mycosis fungoides patient presenting with erythroderma specially requires a careful assessment of the peripheral blood. Studies such as CD markers can lead to a more accurate dia...
متن کامل